SMURF: soft-segmentation for single-cell reconstruction and topological analysis of spatial transcriptomic data

High-resolution spatial transcriptomics requires computational methods to accurately assign transcripts to individual cells. We present SMURF (Segmentation and Manifold UnRolling Framework), a cross-platform soft-segmentation algorithm that uses deep learning to map mRNAs from capture spots to nearb…

View Post on Scour ↗

More from Nature on Scour.